Associate Scientist Job Listing at Kelly Services in Cambridge, MA (Job ID 9560425)

Description

Kelly Science is seeking an Associate Scientist for a growing client located in Cambridge, MA
Position Summary
Kelly Science is seeking a highly motivated Associate Scientist to join the Platform Technology Group. In this role, you will use various CRISPR delivery systems to execute high-throughput screens, and extract samples for NGS (DNA), RT-ddPCR (RNA) and protein (flow or Western blots/Jess automated blots) readouts to identify lead guides across our internal and external programs.  You will track screens through the LIMs and document in your ELN and be responsible for the analysis and summary of the screens to inform follow-up experiments. An ideal candidate should have a strong background in immortalized (hepatocytes) and primary cell culture (HSC, T cells) and have experience screening in these cell types using various CRISPR delivery systems, including RNPs and LNPs.
Key Responsibilities:

• As the Associate Scientist I, Platform Technology, you will be responsible for:
• Lead guide design, screening and selection of lead guide using editing and/or function assays for internal and external partner programs.  
• Analyze and summarize screening results into proper documentation (ELN, Study Reports) 
• Implementation of a high-through LNP screening workflow, including automated LNP-formulations 
• Assist with RNP complexation and perform QC for internal program use 

The ideal candidate will possess:

• B.S. in Cell Biology, or related field with 5+ years of relevant experience in industry; or M.S. in Cell or Mlecular Biology with 2+ years of relevant experience in industry 
• Independently design and run screening experiments, extract gDNA, submit for sequencing, analyze, and present data 
• Experience with mammalian cell culture, including immortalized and primary cells (ex. Liver Cells and HSCs) 
• Proficient in executing and analyzing functional assays including flow cytometry and western blots 
• Experience working with different screening modalities such as guide RNAs and LNPs and knowing how to formulate both RNP and LNPs 
• Experience with data analysis software such as PRISM, Tableau, and FlowJo  
• Familiar in molecular biology analyses such as qPCR and ddPCR 
• Familiar working with lab automation including both liquid handling robots (Biomek I7s, Mantis, Echo) and plate readers (Envision) 
• Excellent communication and interpersonal skills fostering effective teamwork 

Interested? Please apply today for immediate consideration!

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As part of our promise to talent, Kelly supports those who work with us through a variety of benefits, perks, and work-related resources. Kelly offers eligible employees voluntary benefit plans including medical, dental, vision, telemedicine, term life, whole life, accident insurance, critical illness, a legal plan, and short-term disability. As a Kelly employee, you will have access to a retirement savings plan, service bonus and holiday pay plans (earn up to eight paid holidays per benefit year), and a transit spending account. In addition, employees are entitled to earn paid sick leave under the applicable state or local plan. Click here for more information on benefits and perks that may be available to you as a member of the Kelly Talent Community.

Why Kelly® Science & Clinical?

Kelly Science & Clinical is your connection to premier scientific and clinical companies looking to hire industry experts just like you. Our team creates expert talent solutions to solve the world's most critical challenges. Every day, we match science professionals with dream jobs that fit their skills, interests, and career goals—it's the way we think job searching should be. Nearly 100 percent of our science recruiters have a professional background and education in science, so we know a thing or two about the science market and how to get your expertise noticed.

About Kelly

Work changes everything. And at Kelly, we're obsessed with where it can take you. To us, it's about more than simply accepting your next job opportunity. It's the fuel that powers every next step of your life. It's the ripple effect that changes and improves everything for your family, your community, and the world. Which is why, here at Kelly, we are dedicated to providing you with limitless opportunities to enrich your life—just ask the 300,000 people we employ each year.

Kelly Services is proud to be an Equal Employment Opportunity and Affirmative Action employer. We welcome, value, and embrace diversity at all levels and are committed to building a team that is inclusive of a variety of backgrounds, communities, perspectives, and abilities. At Kelly, we believe that the more inclusive we are, the better services we can provide. Requests for accommodation related to our application process can be directed to Kelly's Human Resource Knowledge Center. Kelly complies with the requirements of California's state and local Fair Chance laws. A conviction does not automatically bar individuals from employment. Kelly participates in E-Verify and will provide the federal government with your Form I-9 information to confirm that you are authorized to work in the U.S.

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