Description
Title: Laboratory Technician - Manufacturing Associate
Job Type:
Regular Company: Health Research, Inc. (HRI) Roswell Park Division Department: Center for Immunotherapy Time Type: Full time Weekly Hours: 40FTE:
1 Shift: First Shift (United States of America) Summary: Join a mission-driven team at the forefront of cutting-edge cell and gene therapies. At Roswell Park's state-of-the-art GMP Engineering & Cell Manufacturing (GEM) Facility, we are pioneering advanced immunotherapies like CAR-T with the goal of transforming patient care.We are seeking a Manufacturing Associate to play a key role in the clinical manufacturing of cell therapy products. This is a hands-on, lab-based position within a dynamic cGMP environment, ideally suited for individuals passionate about cellular therapeutics and high-impact translational research.
Key Responsibilities:
• Execute end-to-end cell manufacturing processes under cGMP conditions to produce clinical-grade CAR-T and other advanced therapy products.
• Collaborate cross-functionally with Manufacturing Sciences, Process Development, and Quality Assurance teams to ensure seamless technology transfer, facility fit assessments, and process risk evaluations.
• Contribute to continuous improvement initiatives to optimize processes and ensure readiness for clinical trial demands and regulatory audits.
• Maintain accurate, real-time documentation to uphold data integrity and traceability in line with cGMP and institutional requirements.
What You'll Bring:
• A strong foundation in cell culture and aseptic technique, ideally in a cGMP or regulated environment.
• A detail-oriented mindset with a commitment to quality and operational excellence.
• Effective communication and teamwork skills to support cross-departmental projects.
• Adaptability and drive to work in a fast-paced, evolving field at the intersection of science and medicine.
Why Roswell Park?
• Be part of a nationally recognized cancer center with a legacy of innovation and patient-centered care.
• Access to world-class facilities, resources, and training to support your professional growth.
• The opportunity to directly contribute to life-saving therapies that make a difference in patients' lives.
Responsibilities:
• Manufacture Cell Therapy Products: Perform end-to-end production activities for CAR-T and other advanced cell therapies in a cGMP-compliant cleanroom setting, following strict protocols and aseptic techniques.
• Execute Unit Operations: Follow approved batch records and SOPs to carry out core processes including cell culture, aseptic processing, and cryopreservation activities.
• Document to cGMP Standards: Maintain real-time, compliant documentation in alignment with Good Documentation Practices (GDP) to ensure full traceability and audit readiness.
• Operate & Maintain Equipment: Set up, operate, and perform routine maintenance on specialized laboratory and production equipment, ensuring consistent and reliable performance.
• Support Documentation & Process Development: Contribute to the review, editing, and approval of SOPs, batch records, protocols, and technical reports to support technology transfer and process improvement.
• Cross-Functional Teamwork: Work collaboratively with GEM teams including Manufacturing Sciences, Quality Assurance, and Process Development to meet production goals and resolve technical challenges.
• Drive Operational Excellence: Actively contribute to continuous improvement initiatives, using insights from day-to-day operations to propose enhancements in efficiency, safety, and compliance.
• Handle Biological Materials Safely: Work with human-derived materials under containment protocols, using appropriate PPE and biosafety procedures.
• Support Flexible Scheduling: Adjust to changes in production schedules and support shifts, as needed, to meet clinical timelines.
• Prepare Materials for Manufacturing: Ensure availability of raw materials, reagents, and components through proper preparation, inventory management, and coordination with materials management.
• Support Audits & Investigations: Participate in internal and external audits, and support deviation and investigation efforts to uphold quality standards.
Behavioral & Professional Competencies:
• Strong interpersonal skills and the ability to communicate clearly across functions and teams.
• Highly organized with the ability to manage multiple tasks and meet tight deadlines.
• Excellent verbal and written communication skills.
• Resourceful and solutions-focused mindset with a strong sense of ownership.
• Adaptable and resilient in a fast-paced, mission-critical setting.
The pay range for this position is $40,413 - $51,716 annually which includes a comprehensive benefits package. The listed pay range reflects the range of potential compensation for this role. The actual offer may vary based on qualifications, skills, and experience Qualifications: Required Education and Experience
1. Bachelor's degree in a science-related field; or
2. Associate's degree in a science-related field and the equivalent of two (2) years of full-time laboratory experience; or
3. High School Diploma or High School Equivalency Diploma and the equivalent of four (4) years of full-time laboratory experience.
NOTE:
Required degrees must have been granted by an accredited school, college or university or one recognized by Roswell Park Comprehensive Cancer Center as following acceptable educational practices.
Preferred Qualifications:
Working knowledge of cGMP standards, including experience with production documentation, batch records, and compliance-driven environments.
Solid foundation in aseptic technique and mammalian cell culture, with a track record of maintaining sterility and culture integrity in high-throughput or regulated settings.
Strong communication skills, with the ability to convey scientific concepts clearly across cross-functional teams; collaborative, articulate, and committed to scientific excellence.
Familiarity with key tools and systems used in clinical and commercial cell therapy production, including CliniMACS Plus/Prodigy, Cocoon, or comparable platforms.
Exceptional attention to detail, especially in documentation, cleanliness, and organization—critical qualities for maintaining reproducibility and regulatory compliance
Equal Employment Opportunity Statement
Roswell Park Cancer Institute Corporation (RPCIC) and Health Research Inc. (HRI) Roswell Park Division believe that all persons are entitled to equal employment opportunities, and we do not discriminate against our employees, applicants or job seekers because of their race, color, religion, sex, sexual orientation, gender identity or expression, national origin, creed, age, disability, pregnancy-related condition, military or veteran status, marital or familial status, domestic violence victim status, citizenship status, genetic information, individual's relationship or association with a member of a protected category or any other protected group status as defined by law.
Affirmative Action/Equal Opportunity Employer/Qualified Individuals with Disabilities/Qualified Protected Veterans
Reasonable Accommodation Request
RPCIC and HRI are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the employment process, please email HR-PayAndBenefits@RoswellPark.org and let us know the nature of your request and your contact information.
Our Core Values
RPCIC and HRI are committed to providing an environment where patients, families, employees and community are treated with courtesy and respect. We support an inclusive environment that nurtures the talents, skills and abilities of each individual to embody and reflect our core values: Innovation, Integrity, Teamwork, Commitment, Compassion and Respect.
Grant Funding
This is a grant-funded position. Compliance with funding requirements such as time and effort reporting, grant deliverables, and contract deliverables is required.
E-Verify Employer
Health Research Inc. (HRI) Roswell Park Division participates in the E-Verify program.
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